Lomberk, G.: search on Z-Library

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1

15 DISRUPTION OF FOXP3-EZH2 INTERACTION BY GENETIC MUTATION OR SIGNALING-INDUCED INACTIVATION REPRESENTS A NOVEL PATHOBIOLOGICAL MECHANISM IN INFLAMMATORY BOWEL DISEASE

Bamidele, Adebowale O., Svingen, Phyllis A., Sagstetter, Mary R., Gonzalez, Michelle, Sarmento, Olga F., Braga Neto, Manuel B., Friton, Jessica J., Kugathasan, Subra, Lomberk, Gwen, Urrutia, Raul A.,

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 131 KB

english, 2018

2

Frequent deletions within FRA7G at 7q31.2 in invasive epithelial ovarian cancer

Haojie Huang, Christopher P. Reed, Aderonke Mordi, Gwen Lomberk, Liang Wang, Viji Shridhar, Lynn Hartmann, Robert Jenkins, David I. Smith

Journal:

Genes, Chromosomes and Cancer

Year:

1999

Language:

english

File:

PDF, 126 KB

english, 1999

3

Nupr1-Aurora Kinase A Pathway Provides Protection against Metabolic Stress-Mediated Autophagic-Associated Cell Death

Hamidi, T., Cano, C. E., Grasso, D., Garcia, M. N., Sandi, M. J., Calvo, E. L., Dagorn, J.-C., Lomberk, G., Urrutia, R., Goruppi, S., Carracedo, A., Velasco, G., Iovanna, J. L.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.81 MB

english, 2012

4

Epigenetic Control of Kit Expression in Murine KitLow Interstitial Cell of Cajal (ICC) Stem Cells and Gastrointestinal Stromal Tumors (GIST)

David T. Asuzu, Cordelia D. McGehee, Yujiro Hayashi, Michael R. Bardsley, Adrienne L. Grzenda, Gwen A. Lomberk, Gianrico Farrugia, Raul A. Urrutia, Tamas Ordog

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 176 KB

english, 2011

5

Primers on Molecular Pathways — Caspase Pathway

Lomberk, Gwen, Urrutia, Raul

Journal:

Year:

2009

Language:

english

File:

PDF, 132 KB

english, 2009

6

Sa1685 Chromatin Remodeling via Sin3-HDAC and Hp1-Hmt Pathways in the Regulation of Oncogenic AKT1

Sharma, Anamay N., Chowdhury, Sonia, Lomberk, Gwen A., DeMars, Cathrine J., Iyer, Prasad G., Limburg, Paul J., Krishnadath, Kausilia K., Wang, Kenneth K., Urrutia, Raul A., Buttar, Navtej

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 52 KB

english, 2013

7

Pancreatitis promotes oncogenic Kras G12D -induced pancreatic transformation through activation of Nupr1

Grasso, Daniel, Garcia, Maria Noé, Hamidi, Tewfik, Cano, Carla, Calvo, Ezequiel, Lomberk, Gwen, Urrutia, Raul, Iovanna, Juan L

Journal:

Molecular & Cellular Oncology

Year:

2014

Language:

english

File:

PDF, 121 KB

english, 2014

8

Disruption of Epigenetic Pathways in Regulatory T Cells by FOXP3 Mutations and Pro-Inflammatory Signals During Inflammatory Bowel Disease

Bamidele, Adebowale O., Svingen, Phyllis, Ramos, Guilherme Piovezani, Sagstetter, Mary, Sarmento, Olga F., Gonzalez, Michelle, Lomberk, Gwen, Urrutia, Raul, Kugathasan, Subra, Faubion, William

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 1.11 MB

english, 2017

9

541 KLF11 Behaves As a Tumor Suppressor in Barrett's Mucosa By Transcriptionally Regulating Procarcinogenic cPLA2a-Mediated PGE2 Synthesis via An EGFR-AKT-Sin3a Pathway

Navtej Buttar, Cathrine J. DeMars, Sumera Ilyas, Zaheer H. Rizvi, Shahrooz Rashtak, Shalini Achra, Gwen A. Lomberk, Raul A. Urrutia

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

10

Angiogenesis

Journal:

Year:

2010

Language:

english

File:

PDF, 57 KB

english, 2010

11

388 IL-1β-STAT3 Mediated Up-Regulation of AKT1 Expression in Barrett's Esophagus: A Potential Link Between Inflammation and Carcinogenesis

Sharma, Anamay N., Chowdhury, Sonia, DeMars, Cathrine J., Lomberk, Gwen A., Lutzke, Lori S., Iyer, Prasad G., Wang, Kenneth K., Krishnadath, Kausilia K., Urrutia, Raul A., Buttar, Navtej

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 241 KB

english, 2013

12

Epigenetics

Journal:

Year:

2007

Language:

english

File:

PDF, 59 KB

english, 2007

13

Primers on Molecular Pathways &ndash; Pain and Opioid Receptors, I

Lomberk, Gwen, Cruciani, Ricardo, Urrutia, Raul

Journal:

Year:

2008

Language:

english

File:

PDF, 118 KB

english, 2008

14

Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis

Cano, C. E., Hamidi, T., Garcia, M. N., Grasso, D., Loncle, C., Garcia, S., Calvo, E., Lomberk, G., Dusetti, N., Bartholin, L., Urrutia, R., Iovanna, J. L.

Journal:

Year:

2014

Language:

english

File:

PDF, 16.60 MB

english, 2014

15

Sofosbuvir (Sovaldi) for hepatitis C virus

Lomberk, Mary, Klibanov, Olga M.

Journal:

The Nurse Practitioner

Year:

2015

Language:

english

File:

PDF, 73 KB

english, 2015

16

Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis

Santofimia-Castaño, Patricia, Lan, Wenjun, Bintz, Jennifer, Gayet, Odile, Carrier, Alice, Lomberk, Gwen, Neira, José Luis, González, Antonio, Urrutia, Raul, Soubeyran, Philippe, Iovanna, Juan

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.13 MB

english, 2018

17

Adventitious shoot regeneration of pear (Pyrusspp.) genotypes

Richard L. Bell, Ralph Scorza, Delores Lomberk

Journal:

Plant Cell, Tissue and Organ Culture

Year:

2012

Language:

english

File:

PDF, 341 KB

english, 2012

18

Patient Advocacy

Journal:

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

19

Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating KrasG12D-induced senescence

Grasso, D, Garcia, M N, Hamidi, T, Cano, C, Calvo, E, Lomberk, G, Urrutia, R, Iovanna, J L

Journal:

Cell Death & Differentiation

Year:

2014

Language:

english

File:

PDF, 2.58 MB

english, 2014

20

IL-17 functions through the novel REG3 -JAK2-STAT3 inflammatory pathway to promote the transition from chronic pancreatitis to pancreatic cancer.

Loncle, C., Bonjoch, L., Folch-Puy, E., Lopez-Millan, M. B., Lac, S., Molejon, M. I., Chuluyan, E., Cordelier, P., Dubus, P., Lomberk, G., Urrutia, R., Closa, D., Iovanna, J. L.

Journal:

Cancer Research

Year:

2015

Language:

english

File:

PDF, 2.62 MB

english, 2015

21

REG3 Plays a Key Role in IL17RA Protumoral Effect--Response

Loncle, C., Bonjoch, L., Folch-Puy, E., Lopez-Millan, M. B., Lac, S., Molejon, M. I., Chuluyan, E., Cordelier, P., Dubus, P., Lomberk, G., Urrutia, R., Closa, D., Iovanna, J. L.

Journal:

Cancer Research

Year:

2016

File:

PDF, 153 KB

2016

22

Mo1879 – Methyltransferase G9A As an Epigenomic Regulator of Intestinal Inflammation

Ramos, Guilherme Piovezani, Sagstetter, Mary R., Neto, Manuel Bonfim Braga, Gaballa, Joseph M., Sarmento, Olga F., Gonzalez, Michelle, Bamidele, Adebowale O., Urrutia, Raul, Lomberk, Gwen, Faubion, Wi

Journal:

Gastroenterology

Year:

2019

File:

PDF, 58 KB

2019

23

Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer

Carla E. Cano, María José Sandí, Tewfik Hamidi, Ezequiel L. Calvo, Olivier Turrini, Laurent Bartholin, Céline Loncle, Véronique Secq, Stéphane Garcia, Gwen Lomberk, Guido Kroemer, Raul Urrutia, Juan L

Journal:

EMBO Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 2.48 MB

english, 2012

24

Chromatin-Remodeling Events Reveal a Novel Paradigm for the Epigenetic Control of Stem Cell Factor (Kitl) Expression in Gastrointestinal Smooth Muscles, Mesenchymal Cells and Stromal Tumors

Yujiro Hayashi, David T. Asuzu, Michael R. Bardsley, Gwen A. Lomberk, Gianrico Farrugia, Raul A. Urrutia, Tamas Ordog

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 44 KB

english, 2011

25

Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression

Adrienne Grzenda, Gwen Lomberk, Phyllis Svingen, Angela Mathison…

Journal:

Epigenetics & Chromatin

Year:

2013

Language:

english

File:

PDF, 2.04 MB

english, 2013

26

Animal models

Journal:

Year:

2006

Language:

english

File:

PDF, 54 KB

english, 2006

27

Su1051 Dietary Macronutrients Alter Erk2-AKT1-PGE2 Pathway in Barrett's Mucosa: Potential Role During Carcinogenesis in Barrett's Epithelium

Elebiary, Ahmed, DeMars, Cathrine J., Chowdhury, Sonia, Lomberk, Gwen A., Urrutia, Raul A., Lutzke, Lori S., Wang, Kenneth K., Prasad, Ganapathy A., Buttar, Navtej

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 124 KB

english, 2012

28

163 KLF11 Displays Antifibrogenic Effects by Transcriptional Silencing of Most of the Collagen Genes in Hepatic Stellate Cells

Virk, Charanjit S., Mathison, Angela J., DeMars, Cathrine J., Shergill, Uday, Liebl, Ann, Lomberk, Gwen A., Yaqoob, Usman, Sodavarapu, Soujanya, Fernandez-Zapico, Martin E., Shah, Vijay, Buttar, Navte

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

29

A NEW MOLECULAR MODEL FOR REGULATING THE TGFβ RECEPTOR II PROMOTER IN PANCREATIC CELLS

Lomberk, Gwen, Zhang, Jin-San, Truty, Mark J., Urrutia, Raul

Journal:

Year:

2008

Language:

english

File:

PDF, 109 KB

english, 2008

30

Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis

Hamidi, Tewfik, Algül, Hana, Cano, Carla Eliana, Sandi, Maria José, Molejon, Maria Inés, Riemann, Marc, Calvo, Ezequiel Luis, Lomberk, Gwen, Dagorn, Jean-Charles, Weih, Falk, Urrutia, Raul, Schmid, Ro

Journal:

Journal of Clinical Investigation

Year:

2012

Language:

english

File:

PDF, 4.69 MB

english, 2012

31

Diabetes

Journal:

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

32

Primers on Molecular Pathways &ndash; Notch

Lomberk, Gwen, Urrutia, Raul

Journal:

Year:

2008

Language:

english

File:

PDF, 113 KB

english, 2008

33

HP1γ, A REGULATOR OF EPIGENETIC GENE SILENCING BY DNA METHYLATION, IS REGULATED BY CHANGES IN NUCLEAR LOCALIZATION IN RESPONSE TO PHOSPHORYLATION.

Lomberk, G., Bensi, D., Urrutia, R.

Journal:

Year:

2004

Language:

english

File:

PDF, 580 KB

english, 2004

34

Functional validation reveals the novel missense V419L variant in TGFBR2 associated with Loeys–Dietz syndrome (LDS) impairs canonical TGF-β signaling

Cousin, Margot A., Zimmermann, Michael T., Mathison, Angela J., Blackburn, Patrick R., Boczek, Nicole J., Oliver, Gavin R., Lomberk, Gwen A., Urrutia, Raul A., Deyle, David R., Klee, Eric W.

Journal:

Molecular Case Studies

Year:

2017

Language:

english

File:

PDF, 1.78 MB

english, 2017

35

Aurora kinase B-phosphorylated HP1α functions in chromosomal instability

Williams, Monique M., Mathison, Angela J., Christensen, Trent, Greipp, Patricia T., Knutson, Darlene L., Klee, Eric W., Zimmermann, Michael T., Iovanna, Juan, Lomberk, Gwen A., Urrutia, Raul A.

Journal:

Year:

2019

Language:

english

File:

PDF, 6.49 MB

english, 2019

36

Sin3: Master scaffold and transcriptional corepressor

Adrienne Grzenda, Gwen Lomberk, Jin-San Zhang, Raul Urrutia

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Year:

2009

Language:

english

File:

PDF, 388 KB

english, 2009

37

407a Oncogenic AKT1 Regulation by Tumor Suppressor KLF11: Implications in Growth Regulation During Neoplastic Transformation in Barrett's Esophagus and Interference by Carcinogenic Bile Acid Dependent Erk2 and PKCa Activation

Sonia Chowdhury, Cathrine J. DeMars, Ahmed Elebiary, Abhayjit Singh, Lori S. Lutzke, Kenneth K. Wang, Gwen A. Lomberk, William A. Faubion, Gaurang Daftary, Raul A. Urrutia, Navtej Buttar

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 65 KB

english, 2012

38

Educational websites — Cell biology I

Journal:

Year:

2005

Language:

english

File:

PDF, 52 KB

english, 2005

39

Sequence-specific Recruitment of Heterochromatin Protein 1 via Interaction with Kruppel-like Factor 11, a Human Transcription Factor Involved in Tumor Suppression and Metabolic Diseases

Lomberk, G., Mathison, A. J., Grzenda, A., Seo, S., DeMars, C. J., Rizvi, S., Bonilla-Velez, J., Calvo, E., Fernandez-Zapico, M. E., Iovanna, J., Buttar, N. S., Urrutia, R.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 4.54 MB

english, 2012

40

Diabetes-Causing Gene, Kruppel-Like Factor 11, Modulates the Antinociceptive Response of Chronic Ethanol Intake

Ou, Xiao-Ming, Udemgba, Chinelo, Wang, Niping, Dai, Xiaoli, Lomberk, Gwen, Seo, Seungmae, Urrutia, Raul, Wang, Junming, Duncan, Jeremy, Harris, Sharonda, Fairbanks, Carolyn A., Zhang, Xiao

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2014

Language:

english

File:

PDF, 364 KB

english, 2014

41

A NEW MOLECULAR MODEL FOR REGULATION OF THE TGFβ RECEPTOR II PROMOTER VIA INTERACTION WITH THE LONG-TERM CHROMATIN REPRESSOR PROTEIN, HP1 WITH THE TUMOR SUPPRESSOR KLF11

Lomberk, G., Zhang, J. S., Truty, M. J., Urrutia, R.

Journal:

Year:

2007

Language:

english

File:

PDF, 748 KB

english, 2007

42

Operative management of locally advanced pancreatic cancer: analysis of the national cancer database

Barnes, C.A., Aldakkak, M., Clarke, C.N., Christians, K.K., George, B., Ritch, P.S., Hall, W.A., Erickson, B., Aburajab, M., Lomberk, G., Urrutia, R., Adsay, N.V., Evans, D.B., Tsai, S.

Journal:

Year:

2018

Language:

english

File:

PDF, 39 KB

english, 2018

43

Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis

Hamidi, Tewfik, Algül, Hana, Cano, Carla Eliana, Sandi, Maria José, Molejon, Maria Inés, Riemann, Marc, Calvo, Ezequiel Luis, Lomberk, Gwen, Dagorn, Jean-Charles, Weih, Falk, Urrutia, Raul, Schmid, Ro

Journal:

Journal of Clinical Investigation

Year:

2012

File:

PDF, 4.69 MB

2012

44

Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine

Lomberk, Gwen, Dusetti, Nelson, Iovanna, Juan, Urrutia, Raul

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 1.01 MB

english, 2019

45

Chemopreventive Potential of Metformin in Barrett's Esophagus

Alireza Faridar, Sonia Chowdhury, Cathrine J. DeMars, Abhayjit Singh, Gwen A. Lomberk, Ganapathy A. Prasad, Paul J. Limburg, Amitabh Chak, Navtej Buttar

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 87 KB

english, 2011

46

HDAC-Mediated Gene Silencing of AKT1 by the Tumor Suppressor KLF11: Implications in Growth Regulation and Bile Salt Mediated Neoplastic Transformation in Barrett's Esophagus

Sonia Chowdhury, Alireza Faridar, Cathrine J. DeMars, Abhayjit Singh, Gwen A. Lomberk, Ganapathy A. Prasad, Raul A. Urrutia, Navtej Buttar

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 227 KB

english, 2011

47

Preclinical testing of a new combinatorial therapy against Aurora A and G9a for the treatment of pancreatic cancer

Lomberk, Gwen, Urrutia, Raul

Journal:

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

48

Societies

Journal:

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

49

Distinct Role of Kruppel-like Factor 11 in the Regulation of Prostaglandin E2 Biosynthesis

Buttar, N. S., DeMars, C. J., Lomberk, G., Rizvi, S., Bonilla-Velez, J., Achra, S., Rashtak, S., Wang, K. K., Fernandez-Zapico, M. E., Urrutia, R.

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 4.01 MB

english, 2010

50

Kruppel-like Factor 11 Differentially Couples to Histone Acetyltransferase and Histone Methyltransferase Chromatin Remodeling Pathways to Transcriptionally Regulate Dopamine D2 Receptor in Neuronal Cells

Seo, S., Lomberk, G., Mathison, A., Buttar, N., Podratz, J., Calvo, E., Iovanna, J., Brimijoin, S., Windebank, A., Urrutia, R.

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 4.45 MB

english, 2012

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